IPFA Presentation Harvey Alter (NIH) about confiming XMRV in ME patients and healthy persons
IPFA Presentation Harvey Alter (NIH) about confiming XMRV in ME patients and healthy persons
We (FDA & NIH) have independently confirmed the Lombardi group findings.
The data in the Lombardi, et al Science manuscript are extremely strong and likely true, despite the controversy. Not only have they detected gag and envelope XMRV sequences, but they have infected prostate cell lines and recovered gamma retrovirus particles and have transmitted XMRV to rhesus macaques by the IV route and demonstrated infectivity
Although blood transmission to humans has not been proved, it is probable
The association with CFS is very strong, but causality not proved
XMRV and related MLVs are in the donor supply with an early prevalence estimate of 3%-7%.
We (FDA & NIH) have independently confirmed the Lombardi group findings