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Immunological Changes After Both Exercise and Activity in Chronic Fatigue Syndrome: A Pilot Study
P. D. White, MD K. E. Nye, PhD A. J. Pinching, DM T. M. Yap, MSc N. Power, MRCPsych V. Vleck, PhD D. J. Bentley, PhD J. M. Thomas, MSc M. Buckland, MRCP J. M. Parkin, MRCP
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Cytokines across the night in chronic fatigue syndrome with and without Fibromyalgia
Clin Vaccine Immunol. 2010 Feb 24. [Epub ahead of print]. Nakamura T, Schwander SK, Donnelly R, Ortega F, Togo F, Broderick G,Yamamoto Y, Cherniack NS, Rapoport D, Natelson BH.
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Kindling and Oxidative Stress as Contributors to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS) is one of the more complex illnesses involving multiple systems within the body. Onset of ME/CFS frequently occurs quickly, and many patients report a prior exposure to a viral infection. This debilitating illness can affect the immune, neuroendocrine, autonomic, and neurologic systems. Abnormal biological findings among some patients have included aberrant ion transport and ion channel activity, cortisol deficiency, sympathetic nervous system hyperactivity, EEG spike waves, left ventricular dysfunction in the heart, low natural killer cell cytotoxicity, and a shift from Th1 to Th2 cytokines. We propose that the kindling and oxidative stress theories provide a heuristic template for better understanding the at times conflicting findings regarding the etiology and pathophysiology of this illness.
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Endogenous Non-Retroviral RNA Virus elements in Mammalian Genomes
Masayuki Horie1*, Tomoyuki Honda1,2*, Yoshiyuki Suzuki3, Yuki Kobayashi3, Takuji Daito1, Tatsuo Oshida4, Kazuyoshi Ikuta1, Patric Jern5, Takashi Gojobori3, John M. Coffin5 & Keizo Tomonag
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Bornavirus enters the genome
A survey of mammalian genomes has unexpectedly unearthed DNA derived from bornaviruses, leading to speculation about the role of these viruses in causing mutations with evolutionary and medical consequences
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Role of Chronic Bacterial and Viral Infections in Neurodegenerative, Neurobehavioral, Psychiatric, Autoimmune and Fatiguing Illnesses
Garth L. Nicolson and Jörg Haier BJMP 2009:2(4) 20-28
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The NO/ONOO- Vicious Cycle Mechanism as the Cause of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
Martin L. Pall*, Professor Emeritus of Biochemistry and Basic Medical Sciences, Washington State University and Research Director, The Tenth Paradigm Research Group
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Why myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) may kill you: disorders in the inflammatory and oxidative and nitrosative stress (IO&NS) pathways may explain cardiovascular disorders in ME/CFS.
Journal: Neuro Endocrinol Lett. 2009 Dec 30;30(6). [Epub ahead of print]. Authors: Maes M, Twisk FN. Maes Clinics, Antwerp, Belgium. Email: crc.mh@telenet.be. NLM Citation: PMID: 20038921
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Abnormalities in pH Handling by Peripheral Muscle and Potential Regulation by the Autonomic Nervous System in Chronic Fatigue Syndrome
David EJ Jones MD PhD 1 , Kieren G Hollingsworth MD PhD 2 , Roy Taylor MD 2 , Andrew M Blamire PhD 2 , Julia L Newton MD PhD 1,3 Institute of Cellular Medicine1 , Newcastle Magnetic Resonance Centre2 3 Institute for Ageing and Health, Newcastle University, UK d.e.j.jones@ncl.ac.uk Correspondence: Professor Julia L Newton Institute for Ageing and Health Medical School Framlington Place Newcastle-upon-Tyne NE2 4HH UK Tel: 0191 2824128 Email: julia.newton@nuth.nhs.uk
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EEG Source Analysis of Chronic Fatigue Syndrome
Pierre Flor-Henrya, John C. Linda and Zoltan J. Kolesb a Alberta Hospital Edmonton, Box 307, Edmonton, Edmonton, Alberta, Canada T5J 2J7 b Department of Electrical and Computer Engineering, University of Alberta, Edmonton, Alberta, Canada
News
- 15.06.2009 Think Tank mentioned on Sky News
- 08.06.2009 Conference on ME/CFS in Stavanger is open for patients and relatives
- 15.07.2010 Danish Conference DVD for sale now!
- 29.06.2010 ESME's Think Tank Panel Calls for Blood Ban
- 23.06.2010 Harvey Alter (NIH) Document with the confirmation of XMRV virus in blood